Myocardial blood flow measurement using DCE-MRI: comparison of region-of-interest and voxelwise analysis
نویسندگان
چکیده
INTRODUCTION Measurement of myocardial blood flow (MBF) with DCE-MRI is conventionally performed on a region-of-interest (ROI) basis: time curves are averaged over a ROI, and tracer kinetic analysis is applied to the ROI curve to derive the MBF [1, 2]. In principle, a voxelwise analysis is more attractive since it produces higher resolution images of MBF and may thus increase the diagnostic power. On the other hand, the lower SNR of single-voxel curves may reduce the accuracy or precision of the measurement. The aim of this study was to investigate whether MBF values from a voxelwise analysis were significantly different from an analysis on ROI basis.
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